Vion Labs// Advanced peptide research
Retatrutide.
Delivered.
Retatrutide — the next-generation triple-agonist peptide (GIP · GLP-1 · Glucagon) — supplied in sublingual and pre-filled research pen formats for controlled laboratory R&D.
- Delivery
- Sublingual
- Active
- Retatrutide 6 mg
- Testing
- Third-party, per batch
The formulation
Engineered to be taken.
The bottle
Retatrutide Sublingual
30 mL amber glass. Pump-metered sublingual spray. 6 mg per dose.
The peptide
A ~4,700 Da peptide
Triple agonist — GIP, GLP-1, and Glucagon receptors, in one molecule.
The dose
2.5 mg per spray
Two sprays under the tongue. That is the whole dose. No syringe, no clinic.
SNEDDS delivery platform
The peptide is only
as good as its delivery.
Retatrutide is a ~4,700 Dalton peptide — too large to survive digestion, too fragile for a pill. Injection works, but it's cold-chain, painful, and clinical. Our proprietary Self-Nanoemulsifying Drug Delivery System reaches the bloodstream a different way.
Nanoemulsion protects the peptide
The SNEDDS platform encapsulates retatrutide the moment it hits saliva, shielding it from enzymatic degradation.
Rapid sublingual uptake
Ultra-fine droplets cross the vascularized oral mucosa directly into systemic circulation.
Bypasses first-pass metabolism
Skips the stomach, skips the liver — the active ingredient reaches the bloodstream intact.
Non-invasive, at-home
No cold chain, no refrigeration reminders, no needles. Two sprays under the tongue.
How it works
Four steps.
No injection.
Two metered sprays under the tongue. Hold for 30 seconds. The nanoemulsion does the rest.
Spray under the tongue
Two metered sprays. Hold for 30 seconds.
Nanoemulsion forms
Peptide-loaded droplets, instantly, on contact with saliva.
Crosses the mucosa
The sublingual lining is highly vascularized — uptake is direct.
Systemic delivery
The active peptide reaches the bloodstream. No injection.
Available now
Order the formulation
Sublingual
Retatrutide Sublingual
The first non-invasive sublingual retatrutide — a triple-agonist peptide delivered under the tongue. No needles.
- 6 mg retatrutide per dose (2.5 mg per spray)
- Triple-agonist peptide — GIP, GLP-1, and Glucagon receptors
- Sublingual SNEDDS nanoemulsion platform — no injection required
- Pharmaceutical-grade excipients (FDA IID-listed)
- Non-irritating, designed for repeated sublingual administration
- 30 mL amber glass bottle · 30-day supply at standard dosing
Preliminary observations
Nine weeks.
One healthy volunteer.
Initial observations from a single healthy volunteer receiving the proprietary sublingual retatrutide formulation over a 63-day period. Alternating dosing: 6 mg twice daily (weeks 1, 3, 5, 7, 9) and 6 mg once daily (weeks 2, 4, 6, 8).
−6 lb
over 63 days
A single healthy volunteer, alternating 6 mg BID and 6 mg QD across nine weeks.
−3.4%
total body weight
From 178 lb (80.7 kg) at baseline to 172 lb (78.0 kg) at day 63.
0
reported GI adverse events
No nausea, vomiting, bloating, or abdominal pain over the observation period.
Placeholder observational data — not a controlled clinical trial and not intended to imply clinical efficacy. Individual results will vary. Replace with peer-reviewed data and appropriate regulatory language before launch.
What is retatrutide?
Retatrutide is an investigational triple-agonist peptide — it activates the GIP, GLP-1, and glucagon receptors. It is being studied for weight and metabolic support and is currently only available in the U.S. as an injectable in clinical trials.How is a sublingual formulation different from an injection?
Injections bypass the stomach by design — they have to, because retatrutide's ~4,700 Da peptide is too fragile to survive digestion. Our SNEDDS platform achieves the same goal a different way: it forms a protective nanoemulsion in the mouth, so the peptide crosses the sublingual mucosa directly into circulation. No needle, no refrigeration, no clinic visit.What is SNEDDS?
Self-Nanoemulsifying Drug Delivery System — a pharmaceutical platform that spontaneously forms ultra-fine droplets on contact with fluid. It is used to deliver drugs (peptides, poorly-soluble small molecules) that would otherwise be degraded or poorly absorbed through the oral route.How do I take it?
Two metered sprays under the tongue, once or twice a day, per your provider's direction. Hold for 30 seconds before swallowing so the peptide has time to cross the mucosa.Is this a substitute for medical care?
No. This product should be used only as part of a supervised metabolic-health plan. Consult a licensed clinician before starting, especially if you are pregnant, nursing, taking medication, or managing a medical condition.Do you ship internationally?
Placeholder — this depends on the jurisdictional model chosen by Vion Labs. Client to finalise shipping regions + jurisdictional restrictions before launch.
Ready when you are
A peptide you can actually take.
Two sprays under the tongue. That's the whole thing.
Standard
Pharmaceutical grade
FDA IID-listed excipients only
Standard
Third-party tested
Independent lab, every batch
Standard
Cold-chain shipping
Temperature-controlled dispatch on every order